Synthesis, and Characterization, and Evaluation of Cellular Effects of the FOL-PEG-g-PEI-GAL Nanoparticles as a Potential Non-Viral Vector for Gene Delivery

In this manuscript, we synthesized the potential non viral vector for gene delivery with proper transfection efficiency and low cytotoxicity. Polyethylenimine (PEI) is a well-known cationic polymer which has high positive surface charge for condensing plasmid DNA. However; it is highly cytotoxic in...

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Bibliographic Details
Main Authors: S. Ghiamkazemi, A. Amanzadeh, R. Dinarvand, M. Rafiee-Tehrani, M. Amini
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2010/863136