Factors to influence the accuracy of albumin adjusted free valproic acid concentration

Background: Therapeutic drug monitoring (TDM) is recommended during treatment with valproic acid (VPA), as is the measurement of free VPA concentration (MfVPA). However, MfVPA is unavailable in many institutions. Based on the highly protein-bound characteristics of VPA, an albumin-adjusted formula h...

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Bibliographic Details
Main Authors: Yu-Ju Tseng, Shih-Ying Huang, Chih-Hsuan Kuo, Chen-Yu Wang, Kuo-Chuan Wang, Chien-Chih Wu
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Journal of the Formosan Medical Association
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664620304277