Eugenia uniflora and Syzygium samarangense extracts exhibit anti-trypanosomal activity: Evidence from in-silico molecular modelling, in vitro, and in vivo studies

Eugenia uniflora and Syzygium samarangense extracts exhibit anti-trypanosomal activity: Evidence from in-silico molecular modelling, in vitro, and in vivo studies

The parasite Trypanosoma brucei is the main cause of the sleeping sickness threatening millions of populations in many African countries. The parasitic infection is currently managed by some synthetic medications, most of them suffer limited activity spectrum and/or serious adverse effects. Some stu...

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Bibliographic Details
Main Authors: Mohamed A.O. Abdelfattah, Mohammed Auwal Ibrahim, Hadiza Lawal Abdullahi, Raphael Aminu, Saad Bello Saad, Sonja Krstin, Michael Wink, Mansour Sobeh
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Eugenia uniflora
Syzygium samarangense
Anti-trypanosomal activity
T. brucei
Docking
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221002936

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http://www.sciencedirect.com/science/article/pii/S0753332221002936

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