TRPV1 activation power can switch an action mode for its polypeptide ligands.

TRPV1 (vanilloid) receptors are activated by different types of stimuli including capsaicin, acidification and heat. Various ligands demonstrate stimulus-dependent action on TRPV1. In the present work we studied the action of polypeptides isolated from sea anemone Heteractis crispa (APHC1, APHC2 and...

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Bibliographic Details
Main Authors: Maxim V Nikolaev, Natalia A Dorofeeva, Margarita S Komarova, Yuliya V Korolkova, Yaroslav A Andreev, Irina V Mosharova, Eugene V Grishin, Denis B Tikhonov, Sergey A Kozlov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5419573?pdf=render