Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain.

Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain.

Suppression of Tumorigenicity 2 (ST2), a member of the interleukin-1 receptor (IL-1R) family, activates type 2 immune responses to pathogens and tissue damage via binding to IL-33. Dysregulated responses contribute to asthma, graft-versus-host and autoinflammatory diseases and disorders. To study ST...

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Bibliographic Details
Main Authors: Chao-Yie Yang, James Delproposto, Krishnapriya Chinnaswamy, William Clay Brown, Shuying Wang, Jeanne A Stuckey, Xinquan Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4703388?pdf=render

Internet

http://europepmc.org/articles/PMC4703388?pdf=render

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