Creatine Alleviates Doxorubicin-Induced Liver Damage by Inhibiting Liver Fibrosis, Inflammation, Oxidative Stress, and Cellular Senescence

Creatine Alleviates Doxorubicin-Induced Liver Damage by Inhibiting Liver Fibrosis, Inflammation, Oxidative Stress, and Cellular Senescence

<b>Background</b>: Treatment with the chemotherapy drug doxorubicin (DOX) may lead to toxicities that affect non-cancer cells including the liver. Supplementing the diet with creatine (Cr) has been suggested as a potential intervention to minimize DOX-induced side effects, but its effect...

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Bibliographic Details
Main Authors: Nouf Aljobaily, Michael J. Viereckl, David S. Hydock, Hend Aljobaily, Tsung-Yen Wu, Raquel Busekrus, Brandon Jones, Jammie Alberson, Yuyan Han
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Nutrients
Subjects:
liver damage
doxorubicin
creatine
oxidative stress
senescence
liver fibrosis
Online Access:https://www.mdpi.com/2072-6643/13/1/41

Internet

https://www.mdpi.com/2072-6643/13/1/41

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