Stress‐induced premature senescence activated by the SENEX gene mediates apoptosis resistance of diffuse large B‐cell lymphoma via promoting immunosuppressive cells and cytokines

Stress‐induced premature senescence activated by the SENEX gene mediates apoptosis resistance of diffuse large B‐cell lymphoma via promoting immunosuppressive cells and cytokines

Abstract Background The underlying cause of relapsed and refractory (r/r) diffuse large B‐cell lymphoma (DLBCL) is usually related to apoptosis resistance to antitumor drugs. The recent years have provided lots of evidence that tumor cells may undergo stress‐induced premature senescence (SIPS) in re...

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Bibliographic Details
Main Authors: Jiyu Wang, Qianshan Tao, Ying Pan, Zhixiang Wanyan, Fengfeng Zhu, Xuanxuan Xu, Huiping Wang, Liuying Yi, Mei Zhou, Zhimin Zhai
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:Immunity, Inflammation and Disease
Subjects:
DLBCL
immunosuppressive cells
SASP
SENEX gene
stress‐induced premature senescence
Online Access:https://doi.org/10.1002/iid3.356

Internet

https://doi.org/10.1002/iid3.356

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