Impaired cognitive discrimination and discoordination of coupled theta–gamma oscillations in Fmr1 knockout mice

Impaired cognitive discrimination and discoordination of coupled theta–gamma oscillations in Fmr1 knockout mice

Fragile X syndrome (FXS) patients do not make the fragile X mental retardation protein (FMRP). The absence of FMRP causes dysregulated translation, abnormal synaptic plasticity and the most common form of inherited intellectual disability. But FMRP loss has minimal effects on memory itself, making i...

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Bibliographic Details
Main Authors: Basma Radwan, Dino Dvorak, André A. Fenton
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Neurobiology of Disease
Subjects:
Fragile X
Neural coordination
Cross-frequency coupling
Phase–amplitude coupling
Theta–gamma comodulation
Spatial cognition
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611630002X

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http://www.sciencedirect.com/science/article/pii/S096999611630002X

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