Classification, substrate specificity and structural features of D-2-hydroxyacid dehydrogenases: 2HADH knowledgebase

Classification, substrate specificity and structural features of D-2-hydroxyacid dehydrogenases: 2HADH knowledgebase

Abstract Background The family of D-isomer specific 2-hydroxyacid dehydrogenases (2HADHs) contains a wide range of oxidoreductases with various metabolic roles as well as biotechnological applications. Despite a vast amount of biochemical and structural data for various representatives of the family...

Full description

Bibliographic Details
Main Authors: Dorota Matelska, Ivan G. Shabalin, Jagoda Jabłońska, Marcin J. Domagalski, Jan Kutner, Krzysztof Ginalski, Wladek Minor
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Evolutionary Biology
Subjects:
D-isomer specific 2-hydroxyacid dehydrogenases
Substrate specificity
Sequence-structure-function relationship
Substrate promiscuity
Molecular evolution
Online Access:http://link.springer.com/article/10.1186/s12862-018-1309-8

Internet

http://link.springer.com/article/10.1186/s12862-018-1309-8

Similar Items