Coagulation Factor Plasma Levels Following Administration of a 4-Factor Prothrombin Complex Concentrate for Rapid Vitamin K Antagonist Reversal in Japanese Patients
ABSTRACT: Background: Four-factor prothrombin complex concentrates (4F-PCCs) have been approved for urgent vitamin K antagonist reversal in Western countries for many years. Ethnicity and genetic variations between populations may influence the pharmacokinetic profile of 4F-PCC treatments. Objectiv...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-01-01
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Series: | Current Therapeutic Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0011393X18300262 |