MiR-502 is the first reported miRNA simultaneously targeting two components of the classical non-homologous end joining (C-NHEJ) in pancreatic cell lines

MiR-502 is the first reported miRNA simultaneously targeting two components of the classical non-homologous end joining (C-NHEJ) in pancreatic cell lines

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Acquired inherited and/or somatic mutations drive its development. In order to prevent the formation of these mutations, precise and immediate repair of any DNA damage is indispensable. Non-homologous end-joining (NHEJ) is the...

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Bibliographic Details
Main Authors: Agnieszka Smolinska, Julia Swoboda, Wojciech Fendler, Markus M. Lerch, Matthias Sendler, Patryk Moskwa
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Heliyon
Subjects:
Cell culture
Cell death
DNA repair
Gene mutation
Chemotherapy
miRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020300323

Internet

http://www.sciencedirect.com/science/article/pii/S2405844020300323

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