Rosiglitazone in the thawing medium improves mitochondrial function in stallion spermatozoa through regulating Akt phosphorylation and reduction of caspase 3.

Rosiglitazone in the thawing medium improves mitochondrial function in stallion spermatozoa through regulating Akt phosphorylation and reduction of caspase 3.

<h4>Background</h4>The population of stallion spermatozoa that survive thawing experience compromised mitochondrial functionality and accelerated senescence, among other changes. It is known that stallion spermatozoa show very active oxidative phosphorylation that may accelerate sperm se...

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Bibliographic Details
Main Authors: José M Ortiz-Rodriguez, Carolina Balao da Silva, Javier Masot, Eloy Redondo, Antonio Gazquez, José A Tapia, Cruz Gil, Cristina Ortega-Ferrusola, Fernando J Peña
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211994

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https://doi.org/10.1371/journal.pone.0211994

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