Episomal vector reprogramming of human umbilical cord blood natural killer cells to an induced pluripotent stem cell line MUSIi013-A

Episomal vector reprogramming of human umbilical cord blood natural killer cells to an induced pluripotent stem cell line MUSIi013-A

Natural killer (NK) cells were isolated from human umbilical cord blood from a healthy newborn and reprogrammed by episomal vectors carrying reprograming factors L-MYC, LIN28, OCT4, SOX2, KLF4, EBNA-1, and shRNA against p53 delivered using nucleofection. The obtained MUSIi013-A human induced pluripo...

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Bibliographic Details
Main Authors: Phatchanat Klaihmon, Sudjit Luanpitpong, Chanchao Lorthongpanich, Chuti Laowtammathron, Supaporn Waeteekul, Papussorn Terbto, Surapol Issaragrisil
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Stem Cell Research
Subjects:
Induced pluripotent stem cell
iPSC
Natural killer cells
Reprogramming
Episomal vectors
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121003196

Internet

http://www.sciencedirect.com/science/article/pii/S1873506121003196

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