Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice

Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice

Purpose: Non-small cell lung cancers (NSCLC) are a heterogeneous group of carcinomas harboring a variety of different gene mutations. We have utilized two distinct genetically engineered mouse models of human NSCLC (adenocarcinoma) to investigate how genetic factors within tumor parenchymal cells in...

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Bibliographic Details
Main Authors: Bradford Alan Perez, A Paiman Ghafoori, Chang-Lung eLee, Samuel M Johnston, Yifan Irene Li, Jacob G Moroshek, Yan eMa, Sayan eMukherjee, Yongbaek eKim, Cristian T Badea, David G Kirsch
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Oncology
Subjects:
Fractionation
genetically engineered mice
p53
tumor cell biology
radiation response
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00072/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00072/full

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