The eukaryotic elongation factor 1A is critical for genome replication of the paramyxovirus respiratory syncytial virus.

The eukaryotic elongation factor 1A is critical for genome replication of the paramyxovirus respiratory syncytial virus.

The eukaryotic translation factor eEF1A assists replication of many RNA viruses by various mechanisms. Here we show that down-regulation of eEF1A restricts the expression of viral genomic RNA and the release of infectious virus, demonstrating a biological requirement for eEF1A in the respiratory syn...

Full description

Bibliographic Details
Main Authors: Ting Wei, Dongsheng Li, Daneth Marcial, Moshin Khan, Min-Hsuan Lin, Natale Snape, Reena Ghildyal, David Harrich, Kirsten Spann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0114447

Internet

https://doi.org/10.1371/journal.pone.0114447

Similar Items