A complex plasma plant sterol locus on mouse chromosome 14 has at least two genes regulating intestinal sterol absorption

A complex plasma plant sterol locus on mouse chromosome 14 has at least two genes regulating intestinal sterol absorption

We previously identified two inbred mouse strains, C57BL/6J and CASA/Rk, with different plasma plant sterol levels. An intercross between these strains revealed a broad plasma plant sterol locus on chromosome 14, which peaked at 17 centimorgan (cM) with a maximum logarithm of the odds score of 9.9....

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Bibliographic Details
Main Authors: Ephraim Sehayek, Yee Yan Fung, Hannah J. Yu, Jan Lembcke, Uta Ceglarek, Daniel Teupser, Joachim Thiery, Dieter Lutjohann, Klaus von Bergmann, Jan L. Breslow
Format: Article
Language:English
Published: Elsevier 2006-10-01
Series:Journal of Lipid Research
Subjects:
cholesterol absorption
bile
genetics
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520434169

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