Alveolar epithelial glycocalyx shedding aggravates the epithelial barrier and disrupts epithelial tight junctions in acute respiratory distress syndrome

Alveolar epithelial glycocalyx shedding aggravates the epithelial barrier and disrupts epithelial tight junctions in acute respiratory distress syndrome

The main pathophysiological mechanism of acute respiratory distress syndrome (ARDS) invovles the increase in alveolar barrier permeability that is primarily caused by epithelial glycocalyx and tight junction (TJ) protein destruction. This study was performed to explore the effects of the alveolar ep...

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Bibliographic Details
Main Authors: Jun Li, Zhijiang Qi, Dongxiao Li, Xiao Huang, Boyang Qi, Jiali Feng, Jianyu Qu, Xiaozhi Wang
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Acute respiratory distress syndrome
Alveolar epithelial glycocalyx
Tight junction proteins
Alveolar barrier
Heparanase
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222031218X

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http://www.sciencedirect.com/science/article/pii/S075333222031218X

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