Binding Affinity and Capacity for the Uremic Toxin Indoxyl Sulfate

Protein binding prevents uremic toxins from removal by conventional extracorporeal therapies leading to accumulation in maintenance dialysis patients. Weakening of the protein binding may enhance the dialytic elimination of these toxins. In ultrafiltration and equilibrium dialysis experiments, diffe...

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Bibliographic Details
Main Authors: Eric Devine, Detlef H. Krieter, Marieke Rüth, Joachim Jankovski, Horst-Dieter Lemke
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/6/2/416