PolyC-binding protein 1 interacts with 5'-untranslated region of enterovirus 71 RNA in membrane-associated complex to facilitate viral replication.

PolyC-binding protein 1 interacts with 5'-untranslated region of enterovirus 71 RNA in membrane-associated complex to facilitate viral replication.

Enterovirus 71 (EV71) is one causative agent of hand, foot, and mouth disease (HFMD), which may lead to severe neurological disorders and mortality in children. EV71 genome is a positive single-stranded RNA containing a single open reading frame (ORF) flanked by 5'-untranslated region (5'U...

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Bibliographic Details
Main Authors: Zhen Luo, Xingchen Dong, Youxing Li, Qi Zhang, Cholho Kim, Yu Song, Lei Kang, Yingle Liu, Kailang Wu, Jianguo Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3906175?pdf=render

Internet

http://europepmc.org/articles/PMC3906175?pdf=render

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