PKG II inhibits EGF/EGFR-induced migration of gastric cancer cells.

BACKGROUND: Our previous research results showed that Type II cGMP dependent protein kinase (PKG II) could block the activation of epidermal growth factor receptor (EGFR) and consequently inhibit the proliferation and the related MAPK/ERK-mediated signal transduction of gastric cancer cell line BGC-...

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Bibliographic Details
Main Authors: Lu Jiang, Ting Lan, Yongchang Chen, Jianrong Sang, Yueying Li, Min Wu, Yan Tao, Ying Wang, Hai Qian, Luo Gu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3627897?pdf=render