Staphylococcus aureus α-Toxin Induces Inflammatory Cytokines via Lysosomal Acid Sphingomyelinase and Ceramides

Staphylococcus aureus α-Toxin Induces Inflammatory Cytokines via Lysosomal Acid Sphingomyelinase and Ceramides

Background/Aims: Staphylococcus aureus (S. aureus) infections are a major clinical problem and range from mild skin and soft-tissue infections to severe and even lethal infections such as pneumonia, endocarditis, sepsis, osteomyelitis, and toxic shock syndrome. Toxins that are released from S. aureu...

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Bibliographic Details
Main Authors: Jie Ma, Erich Gulbins, Michael J. Edwards, Charles C. Caldwell, Martin Fraunholz, Katrin Anne Becker
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Staphylococcus aureus
Sphingomyelinase
Ceramide, toxins
Macrophages
Cytokines
Online Access:https://www.karger.com/Article/FullText/484296

Internet

https://www.karger.com/Article/FullText/484296

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