Interaction of PICK1 with C-Terminus of Growth Hormone–Releasing Hormone Receptor (GHRHR) Modulates Trafficking and Signal Transduction of Human GHRHR

Release of growth hormone (GH) from the somatotroph is regulated by binding GH-releasing hormone (GHRH) to its cognate receptor (GHRHR), one of the members of the G protein–coupled receptor (GPCR) superfamily. Proteins bound to the carboxy (C)-terminus of GPCR have been reported to regulate intracel...

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Bibliographic Details
Main Authors: Yuriko Katsushima, Takeya Sato, Chika Yamada, Moe Ito, Yuki Suzuki, Eishin Ogawa, Izumi Sukegawa, Jun Sukegawa, Kohji Fukunaga, Teruyuki Yanagisawa
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319303111