The Functional Role of Zinc Finger E Box-Binding Homeobox 2 (Zeb2) in Promoting Cardiac Fibroblast Activation

The Functional Role of Zinc Finger E Box-Binding Homeobox 2 (Zeb2) in Promoting Cardiac Fibroblast Activation

Following cardiac injury, fibroblasts are activated and are termed as myofibroblasts, and these cells are key players in extracellular matrix (ECM) remodeling and fibrosis, itself a primary contributor to heart failure. Nutraceuticals have been shown to blunt cardiac fibrosis in both in-vitro and in...

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Bibliographic Details
Main Authors: Fahmida Jahan, Natalie M. Landry, Sunil G. Rattan, Ian M. C. Dixon, Jeffrey T. Wigle
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
Zeb2
cardiac fibroblast
activated myofibroblast
cardiac fibrosis
fibroblast contractility
Online Access:http://www.mdpi.com/1422-0067/19/10/3207

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http://www.mdpi.com/1422-0067/19/10/3207

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