Differential Regulation of Escherichia coli fim Genes following Binding to Mannose Receptors

Regulation of the uropathogenic Escherichia coli (UPEC) fimB and fimE genes was examined following type 1 pili binding to mannose-coated Sepharose beads. Within 25 min after mannose attachment, fimE expression dropped eightfold, whereas fimB transcription increased about two- to fourfold. Because bo...

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Bibliographic Details
Main Authors: William R. Schwan, Michael T. Beck, Chia S. Hung, Scott J. Hultgren
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Pathogens
Online Access:http://dx.doi.org/10.1155/2018/2897581