Zeb2 Regulates Myogenic Differentiation in Pluripotent Stem Cells

Zeb2 Regulates Myogenic Differentiation in Pluripotent Stem Cells

Skeletal muscle differentiation is triggered by a unique family of myogenic basic helix-loop-helix transcription factors, including MyoD, MRF-4, Myf-5, and Myogenin. These transcription factors bind promoters and distant regulatory regions, including E-box elements, of genes whose expression is rest...

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Bibliographic Details
Main Authors: Ester Sara Di Filippo, Domiziana Costamagna, Giorgia Giacomazzi, Álvaro Cortés-Calabuig, Agata Stryjewska, Danny Huylebroeck, Stefania Fulle, Maurilio Sampaolesi
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
pluripotent stem cells
myogenic progenitors
Zinc finger E-box-binding homeobox 2
myogenic differentiation
skeletal muscle
signalling pathways
Online Access:https://www.mdpi.com/1422-0067/21/7/2525

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https://www.mdpi.com/1422-0067/21/7/2525

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