The role of viral particle integrity in the serological assessment of foot-and-mouth disease virus vaccine-induced immunity in swine.

The role of viral particle integrity in the serological assessment of foot-and-mouth disease virus vaccine-induced immunity in swine.

The efficacy of foot-and-mouth disease virus (FMDV) inactivated vaccines is mainly dependent on the integrity of the whole (146S) viral particles. If the intact capsids disassemble to 12S subunits, antibodies against internal-not protective epitopes, may be induced. Serological correlates with prote...

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Bibliographic Details
Main Authors: Florencia Celeste Mansilla, Cecilia Soledad Turco, María Cruz Miraglia, Fernando Aníbal Bessone, Raúl Franco, Mariano Pérez-Filgueira, Juan Manuel Sala, Alejandra Victoria Capozzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232782

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https://doi.org/10.1371/journal.pone.0232782

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