Sophocarpine Suppresses NF-κB-Mediated Inflammation Both In Vitro and In Vivo and Inhibits Diabetic Cardiomyopathy

Sophocarpine Suppresses NF-κB-Mediated Inflammation Both In Vitro and In Vivo and Inhibits Diabetic Cardiomyopathy

Diabetic cardiomyopathy (DCM) is a leading cause of mortality in patients with diabetes. DCM is a leading cause of mortality in patients with diabetes. We used both in vitro and in vivo experiments to investigate the hypothesis that sophocarpine (SPC), a natural quinolizidine alkaloid derived from...

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Bibliographic Details
Main Authors: Fang Zou, Ling Wang, Han Liu, Wei Wang, Longlong Hu, Xiaoying Xiong, Lijuan Wu, Yunfeng Shen, Renqiang Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
Subjects:
sophocarpine
NF-κB
inflammation
diabetes
cardiomyopathy—diagnostics
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01219/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01219/full

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