Modulation of extracellular matrix proteins and hepatate stellate cell activation following gadolinium chloride induced Kuffer cell blockade in an experimental model of liver fibrosis/cirrhosis

Hepatic fibrosis is now regarded as a common response to chronic liver injury; regardless of its nature (viral infections, alcohol abuse and metal overload). It is also characterized by excessive deposition of extracellular matrix (ECM) components. The ECM is a dynamic complex of macromolecules that...

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Bibliographic Details
Main Authors: Nilgün Tekkesin, Yaz Taga, Aydın Sav, Süheyla Bozkurt
Format: Article
Language:English
Published: HBKU Press 2013-06-01
Series:QScience Connect
Online Access:http://www.qscience.com/doi/pdf/10.5339/connect.2013.17