Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort.

BACKGROUND:The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), result from the combined effects of susceptibility genes and environmental factors. Previous studies have shown that polymorphisms in the Toll-like receptor (TLR), the apoptosis, the IL-23/IL-17...

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Main Authors: Steffen Bank, Paal Skytt Andersen, Johan Burisch, Natalia Pedersen, Stine Roug, Julied Galsgaard, Stine Ydegaard Turino, Jacob Broder Brodersen, Shaista Rashid, Britt Kaiser Rasmussen, Sara Avlund, Thomas Bastholm Olesen, Hans Jürgen Hoffmann, Bjørn Andersen Nexø, Jacob Sode, Ulla Vogel, Vibeke Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4689491?pdf=render