Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort.
BACKGROUND:The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), result from the combined effects of susceptibility genes and environmental factors. Previous studies have shown that polymorphisms in the Toll-like receptor (TLR), the apoptosis, the IL-23/IL-17...
Main Authors: | Steffen Bank, Paal Skytt Andersen, Johan Burisch, Natalia Pedersen, Stine Roug, Julied Galsgaard, Stine Ydegaard Turino, Jacob Broder Brodersen, Shaista Rashid, Britt Kaiser Rasmussen, Sara Avlund, Thomas Bastholm Olesen, Hans Jürgen Hoffmann, Bjørn Andersen Nexø, Jacob Sode, Ulla Vogel, Vibeke Andersen |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4689491?pdf=render |
Similar Items
-
Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of inflammatory bowel disease in a Danish cohort.
by: Steffen Bank, et al.
Published: (2014-01-01) -
Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis
by: Jacob Sode, et al.
Published: (2018-09-01) -
Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis.
by: Jacob Sode, et al.
Published: (2015-01-01) -
Anti-TNF treatment response in rheumatoid arthritis patients is associated with genetic variation in the NLRP3-inflammasome.
by: Jacob Sode, et al.
Published: (2014-01-01) -
The Functional Overlap of Enforcement and Implementation Tools
by: Stine Andersen
Published: (2007-12-01)