Single-cell analysis reveals congruence between kidney organoids and human fetal kidney

Abstract Background Human kidney organoids hold promise for studying development, disease modelling and drug screening. However, the utility of stem cell-derived kidney tissues will depend on how faithfully these replicate normal fetal development at the level of cellular identity and complexity. Me...

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Bibliographic Details
Main Authors: Alexander N. Combes, Luke Zappia, Pei Xuan Er, Alicia Oshlack, Melissa H. Little
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Genome Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13073-019-0615-0