Targeting microRNA-134 for seizure control and disease modification in epilepsy

MicroRNA-134 is a brain-enriched small noncoding RNA that has been implicated in diverse neuronal functions, including regulating network excitability. Increased expression of microRNA-134 has been reported in several experimental epilepsy models and in resected brain tissue from temporal lobe epile...

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Bibliographic Details
Main Authors: Gareth Morris, Cristina R. Reschke, David C. Henshall
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419304438