Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis

Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis

Hyperhomocysteinemia (HHcy) plays an important role in the progression of many kidney diseases; however, the relationship between HHcy and ischemia-reperfusion injury (IRI)-induced acute kidney injury (IRI-induced AKI) is far from clear. In this study, we try to investigate the effect and possible m...

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Bibliographic Details
Main Authors: Zhang Mei, Yuan Jing, Dong Rong, Da Jingjing, Li Qian, Hu Ying, Yu Fangfang, Ran Yan, Zha Yan, Long Yanjun
Format: Article
Language:English
Published: De Gruyter 2021-05-01
Series:Open Life Sciences
Subjects:
hyperhomocysteinemia
ischemia-reperfusion injury
acute kidney injury
oxidative stress
jnk signaling pathway
Online Access:https://doi.org/10.1515/biol-2021-0054

Internet

https://doi.org/10.1515/biol-2021-0054

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