Lack of genetic interaction between Tbx20 and Tbx3 in early mouse heart development.

Members of the T-box family of transcription factors are important regulators orchestrating the complex regionalization of the developing mammalian heart. Individual mutations in Tbx20 and Tbx3 cause distinct congenital heart abnormalities in the mouse: Tbx20 mutations result in failure of heart loo...

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Bibliographic Details
Main Authors: Svetlana Gavrilov, Richard P Harvey, Virginia E Papaioannou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3723716?pdf=render