Molecular Basis of Tumor Heterogeneity in Endometrial Carcinosarcoma

Molecular Basis of Tumor Heterogeneity in Endometrial Carcinosarcoma

Endometrial carcinosarcoma (ECS) represents one of the most extreme examples of tumor heterogeneity among human cancers. ECS is a clinically aggressive, high-grade, metaplastic carcinoma. At the morphological level, intratumor heterogeneity in ECS is due to an admixture of epithelial (carcinoma) and...

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Bibliographic Details
Main Authors: Susanna Leskela, Belen Pérez-Mies, Juan Manuel Rosa-Rosa, Eva Cristobal, Michele Biscuola, María L. Palacios-Berraquero, SuFey Ong, Xavier Matias-Guiu Guia, José Palacios
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
uterine carcinosarcoma
endometrial carcinoma
metaplastic carcinoma
epithelial-to-mesenchymal transition
clonality
mutation
<i>TP53</i>
PI3K/AKT pathway
gene expression
miRNA expression
Online Access:https://www.mdpi.com/2072-6694/11/7/964

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https://www.mdpi.com/2072-6694/11/7/964

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