Regional differences in susceptibiity of bronchial epithelium to mesenchymal transition and inhibition by the macrolide antibiotic azithromycin.

<h4>Objective</h4>Dysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the injured epithelial cells (epithelial to mesenchymal transition, EMT) may serve as a source of fibrosis. The macrolide ant...

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Bibliographic Details
Main Authors: Balarka Banerjee, Michael Musk, Erika N Sutanto, Stephanie T Yerkovich, Peter Hopkins, Darryl A Knight, Suzanna Lindsey-Temple, Stephen M Stick, Anthony Kicic, Daniel C Chambers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284981/?tool=EBI