Cardioprotective effects of a novel hydrogen sulfide agent-controlled release formulation of S-propargyl-cysteine on heart failure rats and molecular mechanisms.

Cardioprotective effects of a novel hydrogen sulfide agent-controlled release formulation of S-propargyl-cysteine on heart failure rats and molecular mechanisms.

OBJECTIVE: Heart failure (HF) is one of the most serious diseases worldwide. S-propargyl-cysteine (SPRC), a novel modulator of endogenous hydrogen sulfide, is proved to be able to protect against acute myocardial ischemia. In order to produce more stable and sustainable hydrogen sulfide, we used con...

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Bibliographic Details
Main Authors: Chengrong Huang, Juntao Kan, Xu Liu, Fenfen Ma, Ba Hieu Tran, Yunzeng Zou, Shujun Wang, Yi Zhun Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706411?pdf=render

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http://europepmc.org/articles/PMC3706411?pdf=render

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