Anti-carbamylated protein antibodies and skin involvement in patients with systemic sclerosis: An intriguing association.

Carbamylation is a post-translational modification that mostly affects proteins with low turnover, such as dermal proteins. Carbamylated proteins accumulate in skin in an age-dependent manner, contributing to tissue alterations. As dermis is affected by systemic sclerosis (SSc) and anti-carbamylated...

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Bibliographic Details
Main Authors: Elvira Favoino, Marcella Prete, Serena Vettori, Addolorata Corrado, Francesco Paolo Cantatore, Gabriele Valentini, Federico Perosa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210023