Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes.

Focal adhesion kinase (FAK) plays an important role in signal transduction pathways initiated at sites of integrin-mediated cell adhesion to the extracellular matrix. Thus, FAK is involved in many aspects of the metastatic process including adhesion, migration and invasion. Recently, several small m...

Full description

Bibliographic Details
Main Authors: Thérèse B Deramaudt, Denis Dujardin, Fanny Noulet, Sophie Martin, Romain Vauchelles, Ken Takeda, Philippe Rondé
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3958421?pdf=render