Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes.

Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes.

Focal adhesion kinase (FAK) plays an important role in signal transduction pathways initiated at sites of integrin-mediated cell adhesion to the extracellular matrix. Thus, FAK is involved in many aspects of the metastatic process including adhesion, migration and invasion. Recently, several small m...

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Bibliographic Details
Main Authors: Thérèse B Deramaudt, Denis Dujardin, Fanny Noulet, Sophie Martin, Romain Vauchelles, Ken Takeda, Philippe Rondé
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3958421?pdf=render

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