Integrative prediction of gene expression with chromatin accessibility and conformation data

Abstract Background Enhancers play a fundamental role in orchestrating cell state and development. Although several methods have been developed to identify enhancers, linking them to their target genes is still an open problem. Several theories have been proposed on the functional mechanisms of enha...

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Bibliographic Details
Main Authors: Florian Schmidt, Fabian Kern, Marcel H. Schulz
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Epigenetics & Chromatin
Subjects:
HiC
Online Access:https://doi.org/10.1186/s13072-020-0327-0