Heterogeneity of Genetic Admixture Determines SLE Susceptibility in Mexican

Heterogeneity of Genetic Admixture Determines SLE Susceptibility in Mexican

Systemic Lupus Erythematosus (SLE) is an autoimmune inflammatory disorder for which Major Histocompatibility Complex (MHC) genes are well identified as risk factors. SLE patients present different clinical phenotypes, which are partly explained by admixture patterns variation among Mexicans. Populat...

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Bibliographic Details
Main Authors: Susana Hernández-Doño, Juan Jakez-Ocampo, José Eduardo Márquez-García, Daniela Ruiz, Víctor Acuña-Alonzo, Guadalupe Lima, Luis Llorente, Víctor Hugo Tovar-Méndez, Rafael García-Silva, Julio Granados, Joaquín Zúñiga, Gilberto Vargas-Alarcón
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Genetics
Subjects:
HLA
Mexican
population genetics
heterogeneity
HLA-DRB1∗03:01
admixture
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.701373/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.701373/full

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