Prenatal treatment prevents learning deficit in Down syndrome model.

Down syndrome is the most common genetic cause of mental retardation. Active fragments of neurotrophic factors release by astrocyte under the stimulation of vasoactive intestinal peptide, NAPVSIPQ (NAP) and SALLRSIPA (SAL) respectively, have shown therapeutic potential for developmental delay and le...

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Bibliographic Details
Main Authors: Maddalena Incerti, Kari Horowitz, Robin Roberson, Daniel Abebe, Laura Toso, Madeline Caballero, Catherine Y Spong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3510191?pdf=render