The oncoprotein and stem cell renewal factor BMI1 associates with poor clinical outcome in oesophageal cancer patients undergoing preoperative chemoradiotherapy

<p>Abstract</p> <p>Background</p> <p>The polycomb group (PcG) family BMI1, acting downstream of the hedgehog (Hh) pathway, plays an essential role in the self-renewal of haematopoietic, neural, and intestinal stem cells, and is dysregulated in many types of cancer. Our...

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Bibliographic Details
Main Authors: Yoshikawa Reigetsu, Tsujimura Tohru, Tao Lihua, Kamikonya Norihiko, Fujiwara Yoshinori
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/12/461