Cytotoxic Activity of Piperazin-2-One-Based Structures: Cyclic Imines, Lactams, Aminophosphonates, and Their Derivatives

Cytotoxic Activity of Piperazin-2-One-Based Structures: Cyclic Imines, Lactams, Aminophosphonates, and Their Derivatives

<i>N</i>-Heterocycles are considered as desirable scaffolds for the development of novel lead compounds for anticancer drug research. Among them, phosphorus-containing amino-derivatives play a crucial role. A series of imines and products of their further reactions with <i>P</i&...

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Bibliographic Details
Main Authors: Jakub Iwanejko, Mahzeiar Samadaei, Matthias Pinter, Daniel Senfter, Sibylle Madlener, Andrzej Kochel, Nataliya Rohr-Udilova, Elżbieta Wojaczyńska
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Materials
Subjects:
aminophosphonates
cyclic imines
cytotoxic activity
Mannich bases
Pudovik reaction
viability assay
Online Access:https://www.mdpi.com/1996-1944/14/9/2138

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https://www.mdpi.com/1996-1944/14/9/2138

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