Schistosoma mansoni-mediated suppression of allergic airway inflammation requires patency and Foxp3+ Treg cells.

The continual rise of asthma in industrialised countries stands in strong contrast to the situation in developing lands. According to the modified Hygiene Hypothesis, helminths play a major role in suppressing bystander immune responses to allergens, and both epidemiological and experimental studies...

Full description

Bibliographic Details
Main Authors: Laura E Layland, Kathrin Straubinger, Manuel Ritter, Eva Loffredo-Verde, Holger Garn, Tim Sparwasser, Clarissa Prazeres da Costa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3744427?pdf=render