A Multimodal Stimulation Cell Culture Bioreactor for Tissue Engineering: A Numerical Modelling Approach

A Multimodal Stimulation Cell Culture Bioreactor for Tissue Engineering: A Numerical Modelling Approach

The use of digital twins in tissue engineering (TE) applications is of paramount importance to reduce the number of in vitro and in vivo tests. To pursue this aim, a novel multimodal bioreactor is developed, combining 3D design with numerical stimulation. This approach will facilitate the reproducib...

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Bibliographic Details
Main Authors: João Meneses, João C. Silva, Sofia R. Fernandes, Abhishek Datta, Frederico Castelo Ferreira, Carla Moura, Sandra Amado, Nuno Alves, Paula Pascoal-Faria
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Polymers
Subjects:
cylindrical perfusion bioreactor
multimodal stimulation
cytotoxicity study
material characterization
bone tissue engineering
finite element analysis
Online Access:https://www.mdpi.com/2073-4360/12/4/940

Internet

https://www.mdpi.com/2073-4360/12/4/940

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