Distinct Cell Surface Expression Patterns of N-Glycosylation Site Mutants of AMPA-Type Glutamate Receptor under the Homo-Oligomeric Expression Conditions

Distinct Cell Surface Expression Patterns of N-Glycosylation Site Mutants of AMPA-Type Glutamate Receptor under the Homo-Oligomeric Expression Conditions

The AMPA-type glutamate receptor (AMPAR) is a homotetrameric or heterotetrameric ion channel composed of various combinations of four subunits (GluA1–4), and its abundance in the synapse determines the strength of synaptic activity. The formation of oligomers in the endoplasmatic reticulum (ER) is c...

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Bibliographic Details
Main Authors: Jyoji Morise, Saki Yamamoto, Ryosuke Midorikawa, Kogo Takamiya, Motohiro Nonaka, Hiromu Takematsu, Shogo Oka
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
AMPA-type glutamate receptor
GluA1
GluA2
N-glycan
Online Access:https://www.mdpi.com/1422-0067/21/14/5101

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https://www.mdpi.com/1422-0067/21/14/5101

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