Running from Disease: Molecular Mechanisms Associating Dopamine and Leptin Signaling in the Brain with Physical Inactivity, Obesity, and Type 2 Diabetes

Running from Disease: Molecular Mechanisms Associating Dopamine and Leptin Signaling in the Brain with Physical Inactivity, Obesity, and Type 2 Diabetes

Physical inactivity is a primary contributor to diseases such as obesity, cardiovascular disease, and type 2 diabetes. Accelerometry data suggest that a majority of US adults fail to perform substantial levels of physical activity needed to improve health. Thus, understanding the molecular factors t...

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Bibliographic Details
Main Authors: Gregory N. Ruegsegger, Frank W. Booth
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Endocrinology
Subjects:
physical activity
physical inactivity
motivation
dopamine
obesity
leptin
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00109/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2017.00109/full

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