IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells

Summary: Interleukin-38 (IL-38) is a cytokine of the IL-1 family with a role in chronic inflammation. However, its main cellular targets and receptors remain obscure. IL-38 is highly expressed in the skin and downregulated in psoriasis patients. We report an investigation in cellular targets of IL-3...

Full description

Bibliographic Details
Main Authors: Yingying Han, Javier Mora, Arnaud Huard, Priscila da Silva, Svenja Wiechmann, Mateusz Putyrski, Christian Schuster, Eiman Elwakeel, Guangping Lang, Anica Scholz, Tatjana Scholz, Tobias Schmid, Natasja de Bruin, Pierre Billuart, Carlo Sala, Harald Burkhardt, Michael J. Parnham, Andreas Ernst, Bernhard Brüne, Andreas Weigert
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719304218